2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate

Sharaxaad Gaaban:

CAS no: 153012-08-9

Waxyaabaha kiimikada: Gemcitabine Intermediates

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Adeegsada

2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate waxaa loo isticmaalaa sida dhexe ee Gemcitabine.
Gemcitabine waa analooga pyrimidine nucleotide, kaas oo iska leh dawooyinka ka hortagga kansarka dheef-shiid kiimikaadka.Waxay ka hortagi kartaa horumarka isku-dhafka DNA-da muddo cayiman, taas oo ah, S-phase.Waxay leedahay sifooyinka spectrum anticancer ballaaran, habka gaarka ah ee ficilka, sunta hoose, aan iska caabin ah oo leh daawooyinka kale ee kiimikaad iyo ma laha meel sare oo sun ah.Maanta, gemcitabine ayaa loo oggolaaday in loo isticmaalo in ka badan 90 waddan, isagoo noqonaya dawada ugu horreysa ee daaweynta kansarka sambabada unugyada yaryar iyo "heerka dahabka" ee daaweynta kansarka ganaca.

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Faa'iidooyinka Isbeddelka Caafimaadka

TECHNOL OGY FAA'IIDOOYINKA
●Cadaadiska Sare ee Katalytic Hydrogenation.Cadaadiska Sare ee Hydrogenolysis Falcelinta .Falcelinta Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
● Falcelinta dib u habeynta
●Go'aanka Chiral
●Heck, Suzuki,Negishi,Sonogashira .Falcelinta Gignard

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Qalabka

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Dacwad- Wadaag

Waxaan caawinay dhowr shirkadood oo dawooyinka gudaha ugu sarreeya, sidaHansoh, Hengrui iyo HEC Pharm.Halkan waxaan ku tusi doonaa qayb iyaga ka mid ah.

Kiiska Koowaad ee Customization:

Cas No.: 110351-94-5

Cabashada Labaad:

Cas No.: 144848-24-8

Kiiska Saddexaad ee Habaynta:

Cas No.: 200636-54-0

Habka iskaashiga

1.Habbee Dhexdhexaadiyeyaasha Cusub ama API-yada.Si la mid ah wadaagista kiisaska kore, macaamiishu waxay leeyihiin dalabaadka Dhexdhexaadiyeyaasha gaarka ah ama API-yada, mana ka heli karaan badeecadaha loo baahan yahay suuqa, ka dib waxaan ku caawin karnaa si aan u habeyno.

2.Habraaca Hagaajinta Alaabta Hore.Kooxdayadu waxay gacan ka geysan doontaa in ay wanaajiso oo ay hagaajiso wax soo saarka noocaas ah oo dariiqa falcelinta ee duugoobay, qiimaha wax soo saarku uu sarreeyo, waxtarkeeduna uu yar yahay.Waxaan ku siin karnaa dukumeenti buuxa oo wareejinta tignoolajiyada iyo hagaajinta habka, ka caawinta macaamiisha wax soo saar hufan.

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Hore: 2-deoxy-2,2-difluoro-3,5-o-dibenzoylribose mesylate

Xiga: 2-deoxy-2',2'-difluoro-3'5'-bis-o-benzoyleytidi ne monohydrochloride

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