3- (1- (Dimethylamino) ethyl] phenol waxaa loo isticmaalaa dhexdhexaadinta Rivastigmine tartrate.
Rivastigmine tartrate waa dawooyinka cudurka Alzheimers rivastigmine, rivastigmine waa physostigmine derivative by Novartis markii ugu horeysay si guul leh u horumariyo magaca ganacsiga Exelon (exelon), molecule oo leh qaab-dhismeedka carbamate, waa nooc ka mid ah amino acid of cholinesterase cerebral xulashada, sidoo kale waa la joojin karaa. The acetylcholinesterase iyo butyrylcholinesterase, cholinergic neurons by dib u dhigista sii daayo hoos u dhac acetylcholine iyo tamarta kor u qaadida cholinergic dareemayaasha, waxay hagaajin kartaa cilladaha shaqada garashada dhexdhexaadin by cholinergic, taas oo hagaajinaysa shaqada garashada ee bukaanka cudurka Alzheimers.Isku-xidhka borotiinka Plasma Rivastigmine waa daciif, si fudud iyada oo loo marayo xannibaadda dhiigga-maskaxda, kaas oo leh heer sare oo xulashada maskaxda.Ma aha oo kaliya in ay si xushmad leh u shaqeyso kiliyaha maskaxda ee sida fudud u saameeyay iyo hippocampus, laakiin sidoo kale waxay si door bidi ah u joojisaa nooca-hoosaadka AChE ee maskaxda, taasoo keentay hoos u dhaca waxtarka xuubka cholinergic durugsan.Rivastigmine in vivo-nolosha badhkeed waa mid gaaban oo dheer oo ficil ah.Si ka duwan tacrine, badeecadan ku jirta hippocampus iyo kortex G1 saamaynta inhibitory enzyme waa ka xoog badan tahay.Rugta daawaynta waallida nooca fudud ama dhexdhexaadka ah, ama cudurka Alzheimers waxa looga shakisan karaa cudurka Alzheimers kiliinik ahaan.
JIN DUN Medical ayaa lehShahaadada ISO oo buuxisa heerarka wax soo saarka GMP, la shaqaaleysiiyay khubarada isku dhafka daroogada ee gudaha iyo dibadda oo leh khibrad qani ah si ay u hagaan R&D ee shirkadda.
TECHNOL OGY FAA'IIDOOYINKA
●Cadaadiska Sare ee Katalytic Hydrogenation.Cadaadiska Sare ee Hydrogenolysis Falcelinta .Falcelinta Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
● Falcelinta dib u habeynta
●Go'aanka Chiral
●Heck, Suzuki,Negishi,Sonogashira .Falcelinta Gignard
Qalabka
Shaybaadhkayagu waxa uu leeyahay qalab tijaabo ah oo kala duwan, sida: NMR (Bruker 400M),HPLC,chiral-HPLC,LC-MS,LC-MS/MS (API 4000),IR,UV,GC,GC-MS, Chromatography, Mikrowave Synthesizer, Parallel Synthesizer, Kalorimitirka Iskaanka Kala Duwan (DSC), Microscope Electron...
Kooxda R&D
Jindun Medical waxay leedahay koox shaqaale R&D ah oo xirfad leh, waxayna shaqaaleysiisaa khubaro badan oo gudaha iyo dibedda ah oo ku takhasusay isku-darka daroogada si ay u hagaan R&D, taasoo ka dhigaysa isku-dhafkayaga mid sax ah oo hufan.
Waxaan caawinay dhowr shirkadood oo dawooyinka gudaha ugu sarreeya, sidaHansoh, Hengrui iyo HEC Pharm.Halkan waxaan ku tusi doonaa qayb iyaga ka mid ah.
Kiiska Koowaad ee Customization:
Cas No.: 110351-94-5
Cabashada Labaad:
Cas No.: 144848-24-8
Kiiska Saddexaad ee Habaynta:
Cas No.: 200636-54-0
1.Habbee Dhexdhexaadiyeyaasha Cusub ama API-yada.Si la mid ah wadaagista kiisaska kore, macaamiishu waxay leeyihiin dalabaadka Dhexdhexaadiyeyaasha gaarka ah ama API-yada, mana ka heli karaan badeecadaha loo baahan yahay suuqa, ka dib waxaan ku caawin karnaa si aan u habeyno.
2.Habraaca Hagaajinta Alaabta Hore.Kooxdayadu waxay gacan ka geysan doontaa in ay wanaajiso oo ay hagaajiso wax soo saarka noocaas ah oo dariiqa falcelinta ee duugoobay, qiimaha wax soo saarku uu sarreeyo, waxtarkeeduna uu yar yahay.Waxaan ku siin karnaa dukumeenti buuxa oo wareejinta tignoolajiyada iyo hagaajinta habka, ka caawinta macaamiisha wax soo saar hufan.
Laga soo bilaabo bartilmaameedyada daroogada ilaa INDs, JIN DUN Medical ayaa ku siinaysaXalka R&D shaqsiyeysan ee hal-joojin ah.
JIN DUN Medical waxay ku adkaysanaysaa abuurista koox riyooyin leh, samaynta alaab sharaf leh, taxadar leh, adag, iyo u bixista dhammaan si ay u noqoto lammaane la aamini karo iyo saaxiibka macaamiisha!