3- (1- (Dimethylamino) ethyl] phenol

3- (1- (Dimethylamino) ethyl] phenol waxaa loo isticmaalaa dhexdhexaadinta Rivastigmine tartrate.
Rivastigmine tartrate waa dawooyinka cudurka Alzheimers rivastigmine, rivastigmine waa physostigmine derivative by Novartis markii ugu horeysay si guul leh u horumariyo magaca ganacsiga Exelon (exelon), molecule oo leh qaab-dhismeedka carbamate, waa nooc ka mid ah amino acid of cholinesterase cerebral xulashada, sidoo kale waa la joojin karaa. The acetylcholinesterase iyo butyrylcholinesterase, cholinergic neurons by dib u dhigista sii daayo hoos u dhac acetylcholine iyo tamarta kor u qaadida cholinergic dareemayaasha, waxay hagaajin kartaa cilladaha shaqada garashada dhexdhexaadin by cholinergic, taas oo hagaajinaysa shaqada garashada ee bukaanka cudurka Alzheimers.Isku-xidhka borotiinka Plasma Rivastigmine waa daciif, si fudud iyada oo loo marayo xannibaadda dhiigga-maskaxda, kaas oo leh heer sare oo xulashada maskaxda.Ma aha oo kaliya in ay si xushmad leh u shaqeyso kiliyaha maskaxda ee sida fudud u saameeyay iyo hippocampus, laakiin sidoo kale waxay doorbidaa inay joojiso qaybta hoose ee AChE ee maskaxda, taasoo keentay hoos u dhac ku yimaada waxtarka waxyeelada cholinergic peripheral.Rivastigmine in vivo-nolosha badhkeed waa mid gaaban oo dheer oo ficil ah.Si ka duwan tacrine, sheygan ku jira hippocampus iyo kortex ee saameynta xannibaadda enzyme G1 ayaa ka xoog badan.Rugta daawaynta waallida nooca fudud ama dhexdhexaadka ah, ama cudurka Alzheimers waxa looga shakisan karaa cudurka Alzheimers kiliinik ahaan.