5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h) -hal hydrochloride

Sharaxaad Gaaban:

CAS no: 115473-15-9

Waxyaabaha kiimikada: Prasugrel Intermediates

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Faahfaahinta Alaabta

Tags Product

Adeegsada

5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h) -hal hydrochloride ayaa loo istcimaalaa dhex dhexaadiyaha Prasugrel.
Prasugrel waa thiophenopyridine antiplatelet oo ay soo saareen Eli Lilly iyo daiichisankyo, oo ah soo saaraha dawooyinka ee Japan.Waa daawo horudhac ah.Waxay samaysaa molecule firfircoon ka dib dheef-shiid kiimikaad iyada oo loo marayo cytochrome P450 ee beerka waxayna ku daraa daaweeyaha P2Y12 ee platelet si ay uga hortagto isku-darka platelet.Daraasadaha caafimaadku waxay caddeeyeen in qiyaasta 60 mg ay leedahay saameyn ka wanaagsan 300 mg qiyaasta caadiga ah iyo 600 mg oo kordhay clopidogrel, taas oo yareyn karta khatarta guud ee wadne qabadka, istaroogga iyo dhimashada cudurrada wadnaha 20%, waxayna leedahay saameyn degdeg ah. , Saamaynta daaweynta wanaagsan, caabbinta daawada wanaagsan iyo bioavailability, iyo sunta hoose.

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Shahaado

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Faa'iidooyinka Isbeddelka Caafimaadka

TECHNOL OGY FAA'IIDOOYINKA
●Cadaadiska Sare ee Katalytic Hydrogenation.Cadaadiska Sare ee Hydrogenolysis Falcelinta .Falcelinta Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
● Falcelinta dib u habeynta
●Go'aanka Chiral
●Heck, Suzuki,Negishi,Sonogashira .Falcelinta Gignard

JIN DUN R&D

Qalabka

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Dacwad- Wadaag

Waxaan caawinay dhowr shirkadood oo dawooyinka gudaha ugu sarreeya, sidaHansoh, Hengrui iyo HEC Pharm.Halkan waxaan ku tusi doonaa qayb iyaga ka mid ah.

Kiiska Koowaad ee Customization:

Cas No.: 110351-94-5

Cabashada Labaad:

Cas No.: 144848-24-8

Kiiska Saddexaad ee Habaynta:

Cas No.: 200636-54-0

Habka iskaashiga

1.Habbee Dhexdhexaadiyeyaasha Cusub ama API-yada.Si la mid ah wadaagista kiisaska kore, macaamiishu waxay leeyihiin dalabaadka Dhexdhexaadiyeyaasha gaarka ah ama API-yada, mana ka heli karaan badeecadaha loo baahan yahay suuqa, ka dib waxaan ku caawin karnaa si aan u habeyno.

2.Habraaca Hagaajinta Alaabta Hore.Kooxdayadu waxay gacan ka geysan doontaa in ay wanaajiso oo ay hagaajiso wax soo saarka noocaas ah oo dariiqa falcelinta ee duugoobay, qiimaha wax soo saarku uu sarreeyo, waxtarkeeduna uu yar yahay.Waxaan ku siin karnaa dukumeenti buuxa oo wareejinta tignoolajiyada iyo hagaajinta habka, ka caawinta macaamiisha wax soo saar hufan.

Laga soo bilaabo bartilmaameedyada daroogada ilaa INDs, JIN DUN Medical ayaa ku siinaysaXalka R&D shaqsiyeysan ee hal-joojin ah.

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Hore: Cyclopropyl 2-fluorobenzyl ketone

Xiga: 2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone

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