Waxaa u go'ay kontoroolka adag iyo shirkadda wax iibsada ee tixgalinta leh, xubnaha shaqaalahayaga khibradda leh ayaa had iyo jeer diyaar u ah inay ka hadlaan dalabaadkaaga oo ay sameeyaan qaar ka mid ah iibsadaha oo dhan farxad si ay u helaan qeexitaan sare 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, Waxaan Waxa aad diyaar u tahay in aad la shaqeyso saaxiibada wanaagsan ee gurigaaga iyo dibadaba oo aad si wada jir ah u samaysato wakhti dheer oo wanaagsan.
U heellan kontoroolka adag ee adag iyo shirkadda wax iibsada ee tixgalinta leh, xubnaha shaqaalahayaga khibradda leh ayaa inta badan diyaar u ah inay ka hadlaan dalabaadkaaga oo ay ka dhigaan farxad buuxda oo iibsadeShiinaha Imidazole iyo Imz, Sannad kasta, qaar badan oo ka mid ah macaamiisheena ayaa booqan doona shirkadeena oo waxay gaari lahaayeen horumar ganacsi oo weyn oo nala shaqeynaya.Waxaan si kal iyo laab ah kuugu soo dhawaynaynaa inaad na soo booqato wakhti kasta, waxaanan si wada jir ah ugu guulaysan doonaa guul weyn oo xagga warshadaha timaha ah.
Dhexdhexaad u ah isku-dhafka allopurinol.
Waa mid ka mid ah taxanaha pyrazole ee 3-amino-4 lagu beddelay.Waxaa loo isticmaali karaa sidii dhexdhexaad ah si loo soo saaro xeryahooda dabiiciga ah ee faa'iido leh, sida allopurinol, mid ka mid ah taxanaha pyrazolopyrimidine, tan dambe tan iyo 1963 Tan iyo markii la isticmaalo kiliinikada, waxay ahayd daawada ugu weyn ee daaweynta gout.Waqtigan xaadirka ah, waxaa jira dhowr siyaabood oo loo yaqaan 'synthesizing'
3-aminopyrazole-4-carboxamide hemisulfate ee Shiinaha, inta badan adoo ka falcelinaya malononitrile iyo triethyl orthoformate si ay u diyaariyaan ethoxymethylene malononitrile, ka dibna falcelinta hydrazine hydrate waxay soo saartaa 3-amino-4-cyanopyrazole, kaas oo ugu dambeyntii ka falceliyay si loo soo saaro sulfuric acid.
3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Kiimikada Warshadaha Times, 2008, 6 (22): 39 40), wadarta guud ee dhalidda Isku-dubarid habkani waa qiyaastii 60% (waxaa lagu xisaabiyaa sida malononitrile), habkani wuxuu ku lug leeyahay falcelin saddex-tallaabo ah, tillaabooyinka waa dheer yihiin, iyo reagents-yada loo isticmaalo, sida malononitrile iyo ethoxymethylene malononitrile, waa sun badan oo qaali ah.Intaa waxaa dheer, 3-aminopyrazole-4 oo ay diyaarisay habkan - Formamide hemisulfate waxay leedahay midab ay adag tahay in la saaro oo u baahan habayn dheeraad ah, taas oo aad u adag.
Waxaa jira warbixino ku jira suugaanta shisheeye iyadoo la adeegsanayo pyridylamide hydrazone iyo ethoxymethylene malononitrile sida alaabta ceeriin si loo helo 3-amino-4-cyanopyrazole marka lagu daro iyo baaskiil wadida, ka dibna ka falcelisa sulfuric acid oo urursan si loo helo xarunta bartilmaameedka (Reuken G Jones. Falcelinta orthoesters leh xeryahooda firfircoon ee methylene [J] J Am Chem Soc. 1952,74 (5) : 4889 4891).Qalabka ugu muhiimsan ee loo isticmaalo habkan waa qaali, wax-soo-saarka fal-celinta ma aha mid sarreeya, faa'iidada wax-soo-saarka warshaduhu waa mid hooseeya.Waa in ay adagtahay.
Heerka fulinta:Heerka Ganacsiga
Dibadda:Cad-cad ama budo jaale ah
Xidhmada:25kg/durbaan
assay (HPLC) ka kooban ama ka weyn 98.0%
daahirnimada (HPLC) ka kooban ama la mid ah 99.5%
Waxaa u go'ay kontoroolka adag iyo shirkadda wax iibsada ee tixgalinta leh, xubnaha shaqaalahayaga khibradda leh ayaa had iyo jeer diyaar u ah inay ka hadlaan dalabaadkaaga oo ay sameeyaan qaar ka mid ah iibsadaha oo dhan farxad si ay u helaan qeexitaan sare 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, Waxaan Waxa aad diyaar u tahay in aad la shaqeyso saaxiibada wanaagsan ee gurigaaga iyo dibadaba oo aad si wada jir ah u samaysato wakhti dheer oo wanaagsan.
Qeexitaan sareShiinaha Imidazole iyo Imz, Sannad kasta, qaar badan oo ka mid ah macaamiisheena ayaa booqan doona shirkadeena oo waxay gaari lahaayeen horumar ganacsi oo weyn oo nala shaqeynaya.Waxaan si kal iyo laab ah kuugu soo dhawaynaynaa inaad na soo booqato wakhti kasta, waxaanan si wada jir ah ugu guulaysan doonaa guul weyn oo xagga warshadaha timaha ah.