Rivaroxaban (S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban (S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Loo isticmaalo bukaanada qaangaarka ah ee leh qalliinka beddelka miskaha ee la doortay ama jilibka si looga hortago xinjirowga dhiigga (VTE).
Waxaa loo isticmaalaa si looga hortago ama loo yareeyo samaynta xinjirowga dhiigga, xinjirowga dhiigga ee qoto dheer (DVT) iyo sambabada sambabada (PE) ka dib qalliinka beddelka miskaha ama jilibka.
Qiyaasta lagu taliyey waa rivaroxaban afka 10mg, hal mar maalintii.Rivaroxaban 10mg waxaa lagu qaadan karaa cunto ama kaligiis.Kiniinada Rivaroxaban 15mg ama 20mg waa in lagu qaataa cunto.
heerka: usp40
Qiimaynta: 99-102%
Dibadda: budo cad
Xidhmada: 25kg / durbaan
Qaado 4-(4-aminophenyl) morpholin-3-hal (SM-1), (S)-N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) .Ka dib markii uumi-baxo, baaskiil-wareejin, aminolysis iyo acylation, rivaroxaban cayriin ayaa la helaa, iyo rivaroxaban dhammaatay waa la safeeyey.
Diyaarinta: Alaabtani waa kaniini dahaarka leh oo casaan ah.
Agabka:
Kiniiniga asaasiga ah: microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, hypromellose, sodium lauryl sulfate, magnesium stearate.
Dahaarka: polyetylen glycol, hypromellose, titanium dioxide, bir oxide cas
Rivaroxaban waa daawo afka laga qaato oo si toos ah u doorta factor Xa.Iyada oo si heer sare ah loo xushay oo loo tartamayo xannibaadda xorta ah iyo xadhigga Xa iyo dhaqdhaqaaqa prothrombin, waxay kordhisaa qayb firfircoon ee saxanka wakhtiga thromboplastin (PT) iyo wakhtiga prothrombin (aPTT) qaab ku-tiirsanaan ah, kaas oo joojin kara qulqulka xinjirowga. waxay joojiyaan soo saarista thrombin iyo thrombosis.Rivaroxaban ma joojiso thrombin (factor activating Ⅱ), mana la xaqiijin in ay saameyn ku yeelato platelets
Farqiga muhiimka ah ee u dhexeeya rivaroxaban iyo fondaparinux/heparin waa in aysan u baahnayn ka-qaybgal antithrombin III oo ay si toos ah uga soo horjeedaan arrin xor ah oo xiran Xa;halka heparin uu u baahan yahay antithrombin III si uu u shaqeeyo, wax saameyn ahna kuma laha factor Xa ee dhismaha prothrombin.
JIN DUN Medical ayaa lehShahaadada ISO oo buuxisa heerarka wax soo saarka GMP, la shaqaaleysiiyay khubarada isku dhafka daroogada ee gudaha iyo dibadda oo leh khibrad qani ah si ay u hagaan R&D ee shirkadda.
TECHNOL OGY FAA'IIDOOYINKA
●Cadaadiska Sare ee Katalytic Hydrogenation.Cadaadiska Sare ee Hydrogenolysis Falcelinta .Falcelinta Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
● Falcelinta dib u habeynta
●Go'aanka Chiral
●Heck, Suzuki,Negishi,Sonogashira .Falcelinta Gignard
Qalabka
Shaybaadhkayagu waxa uu leeyahay qalab tijaabo ah oo kala duwan, sida: NMR (Bruker 400M),HPLC,chiral-HPLC,LC-MS,LC-MS/MS (API 4000),IR,UV,GC,GC-MS, Chromatography, Mikrowave Synthesizer, Parallel Synthesizer, Kalorimitirka Iskaanka Kala Duwan (DSC), Microscope Electron...
Kooxda R&D
Jindun Medical waxay leedahay koox shaqaale R&D ah oo xirfad leh, waxayna shaqaaleysiisaa khubaro badan oo gudaha iyo dibedda ah oo ku takhasusay isku-darka daroogada si ay u hagaan R&D, taasoo ka dhigaysa isku-dhafkayaga mid sax ah oo hufan.
Waxaan caawinay dhowr shirkadood oo dawooyinka gudaha ugu sarreeya, sidaHansoh, Hengrui iyo HEC Pharm.Halkan waxaan ku tusi doonaa qayb iyaga ka mid ah.
Kiiska Koowaad ee Customization:
Cas No.: 110351-94-5
Cabashada Labaad:
Cas No.: 144848-24-8
Kiiska Saddexaad ee Habaynta:
Cas No.: 200636-54-0
1.Habbee Dhexdhexaadiyeyaasha Cusub ama API-yada.Si la mid ah wadaagista kiisaska kore, macaamiishu waxay leeyihiin dalabaadka Dhexdhexaadiyeyaasha gaarka ah ama API-yada, mana ka heli karaan badeecadaha loo baahan yahay suuqa, ka dib waxaan ku caawin karnaa si aan u habeyno.
2.Habraaca Hagaajinta Alaabta Hore.Kooxdayadu waxay gacan ka geysan doontaa in ay wanaajiso oo ay hagaajiso wax soo saarka noocaas ah oo dariiqa falcelinta ee duugoobay, qiimaha wax soo saarku uu sarreeyo, waxtarkeeduna uu yar yahay.Waxaan ku siin karnaa dukumeenti buuxa oo wareejinta tignoolajiyada iyo hagaajinta habka, ka caawinta macaamiisha wax soo saar hufan.
Laga soo bilaabo bartilmaameedyada daroogada ilaa INDs, JIN DUN Medical ayaa ku siinaysaXalka R&D shaqsiyeysan ee hal-joojin ah.
JIN DUN Medical waxay ku adkaysanaysaa abuurista koox riyooyin leh, samaynta alaab sharaf leh, taxadar leh, adag, iyo u bixista dhammaan si ay u noqoto lammaane la aamini karo iyo saaxiibka macaamiisha!
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